FROZEN SECTION DIAGNOSIS: AN EXPERIENCE AT THE INSTITUTE (CHUGHTAI’S LAHORE LAB, LAHORE)

  • DR. MUHAMMAD FAYYAZ ANWAR Post Graduate Medical Institution, Lahore
  • DR. MUHAMMAD IRFAN BASHEER Postgraduate Medical Institute, Lahore
  • DR. SADIA RANA Services Institute of Medical Sciences, Lahore
  • DR. NAJAM-ULHASNAIN Postgraduate Medical Institute, Lahore General Hospital, Lahore
  • DR. HASEEB AHMED KHAN FMH College of Medicine and Dentistry, Lahore
  • DR. IQBAL AHMED Post Graduate Medical Institution, Lahore
  • DR. MUHAMMAD KASHIF MUGHAL Postgraduate Medical Institute, Lahore
Keywords: Frozen Section, Histopathology, Surgical Pathology, Biopsy

Abstract

Background: Frozen section based histological diagnosis is required by the surgeon(s) to make immediate intraoperative decision(s) So, high accuracy of frozen section is important for the reporting surgical pathologist(s) and surgeon(s) to make subsequent on-table decision for the management of the patient.

Objective: To assess the concordance of frozen section histological diagnosis reported in our institute by comparing it with subsequent final histological diagnosis.

Material & Methods: Biopsy specimens 100 patients submitted for frozen section diagnosis were included in the study. The diagnosis rendered on fresh frozen section was compared with the diagnosis rendered on paraffinembedded formalin-fixed section of the same specimen.

Results: Male-to-female ratio of the patients included in the study was 2:1 with mean age of 48.70 years. The diagnosis could be rendered in 99 cases, while in 1 case diagnosis was deferred to permanent sections (deferral rate: 1%). There was no difference found between the frozen section diagnosis and the final diagnosis in 97 (concordance rate: 97.9%) cases.

Conclusion: Frozen section-based histological assessment for diagnosis and/or surgical resection margins status is a reliable technique in terms of its timely and accurate reporting and low deferral rate.

Author Biographies

DR. MUHAMMAD FAYYAZ ANWAR, Post Graduate Medical Institution, Lahore

Assistant Professor of Pathology Department

DR. SADIA RANA, Services Institute of Medical Sciences, Lahore

Post Graduate Resident, Department of Obstetrics and Gynecology

DR. NAJAM-ULHASNAIN, Postgraduate Medical Institute, Lahore General Hospital, Lahore

Professor of ENT/Head & Neck Surgery

DR. HASEEB AHMED KHAN, FMH College of Medicine and Dentistry, Lahore

Assistant Professor of Pathology Department

DR. IQBAL AHMED, Post Graduate Medical Institution, Lahore

Senior Demonstrator of Pathology Department

DR. MUHAMMAD KASHIF MUGHAL, Postgraduate Medical Institute, Lahore

Senior Demonstrator of Pathology Department

Published
2018-09-01