A STUDY OF DEMOGRAPHIC PROFILE ASSOCIATION WITH SEROPOSITIVE CASES OF DENGUE VIRUS INFECTION IN LAHORE

Abstract

Introduction: Dengue fever is caused by a flavi virus, called dengue virus. Aedes Egypti and Aedes Albopictus transmit this virus. Diagnosis is through direct i.e. virus isolation, genome detection and antigen detection and indirect i.e. serology IgG and IgM detection methods.

Objective: The objective of the study was to study the association of different epidemiological factors with dengue fever in Lahore.

Material and Methods: 300 suspected dengue cases presenting in Emergency, Dengue isolation ward, different wards and OPD’s of Mayo Hospital, Sir Ganga Ram Hospital and Jinnah Hospital Lahore were obtained.

Sampling: Convenience purposive sampling was opted.

Study Design: It was analytical cross sectional. The different demographic and epidemiological factors were noted to see their association with dengue fever.

Results: 90 patients (30% of total) were positive for IgM and 210(70 % of total) were negative for IgM. 108 patients (36% of total)were positive for IgG and 192(64% of total) were negative for IgG . 54 (18%) were positive for IgM and 63 (21%) males were positive for IgG. 36 females (12%) were positive for IgM and 45 (15%) females were positive for IgG. Simultaneous positivity of both IgG and IgM was in 18 male patients (6%) and in 21 female patients (7%). IgM positivity was more in age group 11-20 (9%) and least in age group 71-80. IgG positivity was more in age group 11-20 (12%) and least in age groups 0-11 and 71-80(2% each). Their mean age were 29.14 + 17.03 (SD) years ranging from 9 months to 90 years? Maximum positivity of IgM and IgG both was observed in Northern Lahore i.e. 48 (19 %). Minimum positivity of both IgM and IgG was observed in Eastern Lahore i.e. 3 (3 %) respectively.