FASTING SERUM GROWTH HORMONE LEVELS IN NEWLY DIAGNOSED PATIENTS OF PULMONARY TUBERCULOSIS WITH AND WITHOUT COEXISTENT DIABETES MELLITUS TYPE2

Abstract

The aim of this cross-sectional comparative study was to determine and compare the serum growth hormone (GH) and fasting blood glucose (FBG) levels in the newly diagnosed patients of pulmonary tuberculosis (TB) with and without diabetes mellitus type2 (DM type 2). Eighty four male subjects where included in this study and divided into three groups. Group 1, healthy controls (n=28), group 2 were patients of pulmonary tuberculosis without DM (n=28) and group three were pulmonary TB patients with newly diagnosed DM type 2 (n=28). Serum GH and fasting blood glucose levels were determined before starting anti-TB treatment in the TB patients and treatment of hyperglycemia in diabetic patients.Statistically significant difference was observed between serum GH and FBG levels of the three study groups.There was a significant difference between serum GH and FBG levels of TB patients with and without diabetes mellitus before starting anti-TB treatment. It is concluded that the hyperglycemic effects of GH on glycemic control should be taken into consideration when treating TB diabetic patients.