EXPRESSION OF C-KIT IN BENIGN AND MALIGNANT ENDOMETRIAL LESIONS

Abstract

Objective: To examine and to compare c-kit expression in benign and malignant endometrial lesions.

Study Design: Comparative, Cross Sectional Study

Place and Duration of Study: Department of Pathology, King Edward Medical University Lahore.

Methodology: Patients undergoing Gynecological procedures (diagnostic dilatation and curettage or hysterectomies due to dysfunctional uterine bleeding). They were further sub classified into benign and malignant lesions. Patients age and histopathological diagnosis were recorded and described.

Conclusion: This study showed, c-kit over expression was seen in 31/68 (45.6%) in endometrial carcinoma and 21/68 (30.9%) in benign endometrial lesions