PREVALENCE OF MALIGNANCY IN SOLITARY NODULES OF THYROID

Abstract

Objective: To ascertain the incidence of cancer in individuals with a single thyroid nodule.

Methods: It is Prospective, Observational, Case Series. Study was conducted at Jinnah Postgraduate Medical Centre, Karachi, Department of ENT, from January 10, 2023, to June 10, 2023. Patients were enrolled if a physical examination revealed a palpable thyroid gland diagnosis. A thorough physical examination and history were documented. Using a pinhole collimator, 99mTc pertechnetate scintigraphy was performed on each patient. The study was open to patients with a single nodule who satisfied the inclusion and exclusion criteria. There was a thyroid ultrasound. Sonographic features were noted, including nodule calcifications, size, hypo echogenicity, and irregular shape.

Results: Ninety-five patients who fulfilled the inclusion criteria were included in the study. The Mean±S.D age of the study population was 48.12+9.457years. The mean duration of the disease was 2.042±0.95years. On analysis of demographics data, it was observed that 57 (60%) were males and 38 (40%) were females. Upon analysis of the frequency of the outcome variables, 11 (11.58%) had malignancy.

Conclusion: Male patients made up the majority and most of them were older than 40. A thyroid gland ultrasound showing an irregular shape and a tumor size larger than 20 cm are linked to a higher risk of cancer.