CLINICAL EFFICACY OF CONVALESCENT PLASMA TREARMENT IN COVID-19 PATIENTS

  • Ghazala Rubi PGMI / LGH / AMC, Lahore, Pakistan
  • Muhammad Sharjeel Ilyas Post graduate medical institute, lahore
  • Ayesha Fahim University College of Dentistry, University of Lahore, Lahore, Pakistan
  • Faisal Hassan Shah Postgraduate Medical Institute / Ameer-ud-Din Medical College,/Lahore General Hospital, Lahore
  • Zainab Javaid
DOI: https://doi.org/10.51642/ppmj.v34i01.538
Keywords: COVID-19, Convalescent Plasma Therapy, Symptoms, Critically ill

Abstract

Background: COVID-19 is an infectious disease caused by a newly identified strain of coronavirus (SARS-CoV-2). This strain is responsible for respiratory infections in humans.

Objective: The objective of this study was to analyze the clinical efficacy and safety of convalescent plasma (CP) therapy in coronavirus disease 2019 (COVID-19) cases.

Methodology: This was an experimental trial of COVID-19 patients treated with convalescent plasma (CP) therapy, these patients were admitted in Lahore General Hospital, Lahore, Pakistan during April 24 to august 24, 2021.

Results: Pearson correlation was applied to extract the efficacy of convalescent plasma therapy (CP). A p-value ≤0.05 was considered significant. 16 out of 20 patients (80%) were completely recovered from COVID-19.

Conclusion: Convalescent plasma (CP) proved to be an effective and safe therapy for confirmed cases of COVID-19. However, two critically ill patients died.

Author Biographies

Ghazala Rubi, PGMI / LGH / AMC, Lahore, Pakistan

Director Central Research Lab 

Muhammad Sharjeel Ilyas, Post graduate medical institute, lahore

Assistant Professor, Department of Oral Biology

 

Ayesha Fahim, University College of Dentistry, University of Lahore, Lahore, Pakistan

Associate professor and HOD Oral Biology Department

 

Faisal Hassan Shah, Postgraduate Medical Institute / Ameer-ud-Din Medical College,/Lahore General Hospital, Lahore

Associate Professor, Department of Biochemistry

Zainab Javaid

Postgraduate Resident

Published
2023-03-06
Issue
Vol 34 No 01 (2023): Pakistan Postgraduate Medical Journal
Section
Article