SALINE INFUSION SONOGRAPHY: A VALID TOOL FOR DETECTION OF INTRAUTERINE PATHOLOGY IN WOMEN WITH ABNORMAL UTERINE BLEEDING

  • Umber Fatima UMDC
  • Anees Fatima University Medical & Dental College Faisalabad
  • Iffat Imran College of Medicine, Taif University KSA
  • Humaira Zafar University Medical & Dental College Faisalabad
  • Mubashra Naz University Medical & Dental College Faisalabad
  • Shakeela Irfan Danat Al Emarat hospital, Abudhabi
Keywords: Uterine cavity lesions, sensitivity, specificity, saline infusion sonography

Abstract

ABSTRACT:

OBJECTIVE:

To evaluate the diagnostic accuracy of transvaginal ultrasound and saline infusion sonography for the detection of intra-cavity lesions of uterus using histopathology on hysterectomy specimens as the gold standard.

STUDY DESIGN:

Cross-sectional (validation) study.

Place & duration of study:

Department of obstetrics & gynecology, Madina Teaching Hospital, Faisalabad from January 18, 2022 to September 30, 2022.

METHODOLOGY:

Sixty patients with abnormal uterine bleeding and postmenopausal bleeding were included in the study. All participants were evaluated by transvaginal ultrasound (TVS) and saline infusion sonography (SIS) to detect uterine cavity pathologies. The findings at TVS and SIS were compared with the findings of histopathology on hysterectomy specimens. Sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy were calculated.

RESULTS:

Mean age was 49.68±5.9 years. Polyps, proliferative endometrium, endometrial hyperplasia and sub mucous fibroid are noted in 32 (53.3%), 16 (26.7%), 3 (5%) and 9 (15%) patients,  Sensitivity, specificity, PPV, NPV and diagnostic accuracy of TVS are 61.36%, 100%, 100%, 48.48% and 71.67% and for SIS are 88.64%, 100%, 100%, 76.19% and 91.67% respectively.

CONCLUSION:

SIS is highly sensitive and specific investigation to detect intra-cavity abnormalities of uterus. SIS can be used as an alternative investigation tool in low resource settings whenever hysteroscopy in not readily available.

KEY WORDS: Uterine cavity lesions, sensitivity, specificity, saline infusion sonography

 

 

Author Biographies

Anees Fatima, University Medical & Dental College Faisalabad

Associate professor, Department of Obstetrics and Gynaecology, UMDC Faisalabad, Pakistan

Iffat Imran, College of Medicine, Taif University KSA

Assistant Professor, Department of Obstetrics and Gynaecology, College of Medicine, Taif University KSA

Humaira Zafar, University Medical & Dental College Faisalabad

Professor, Department of Obstetrics and Gynaecology, UMDC Faisalabad.

Mubashra Naz, University Medical & Dental College Faisalabad

Professor, Department of Obstetrics and Gynaecology, UMDC Faisalabad.

Shakeela Irfan, Danat Al Emarat hospital, Abudhabi

Consultant Physician, Department of Obstetrics and Gynaecology, Danat Al Emarat hospital, Abudhabi

Published
2023-12-30