USEFULNESS OF PLATELET COUNT AND MEAN PLATELET VOLUME IN PREDICTION OF PREECLAMPSIA

Abstract

Objectives: The present study was designed to evaluate the usefulness of platelet count (PC) and mean platelet volume (MPV) in the prediction of preeclampsia.

Study design: It is a cross-sectional prospective study.

Place of study: Pathology department Allama Iqbal medical college/Jinnah Hospital Lahore

Patients and Methods: A total number of 140 pregnant females in third trimester from gynecology and obstetrics department were included in the study. Eighty subjects were diagnosed cases of preeclampsia labeled as group I while in group II there were 60 healthy pregnant females. Complete blood count (CBC) was performed on sysmex kx-21 to see the platelet count and mean platelet volume.

Results: Platelet count was found to be decreased in subjects with preeclampsia as compared to controls and a statistically significant difference was observed with a (P-value of < 0.001) in pregnant females having preeclampsia than normal normotensive subjects. While mean paltelet volume was found to be increased in preaclampsia patient as compared to normal subjects (P-value of < 0.001).

Conclusion: The present study suggest that decreased Platelet count and increased mean platelet volume is associated with preeclampsia. Compete blood count is simple and cost effective test which can help the clinician in prediction and diagnosis of preeclampsia in the developing country like ours with limited resources.