FREQUENCY OF RAISED CRP IN ACUTE HEART FAILURE

Abstract

C-reactive protein (CRP) is a marker for cardiovascular and cerebrovascular diseases. It is also proven that it has role in long-term development of heart failure and mortality in patients with cardiovascular diseases.

Objective: To analyze the CRP levels in patients presenting with acute heart failure and determine the frequency of patients with raised CRP levels.

Material and Methods: This cross-sectional study was conducted at Punjab Institute of Cardiology for a period of six months after approval from the hospital ethical committee. Three hundred and forty-five patients presenting with acute heart failure were taken. After Informed consent, their venous blood samples were drawn for measurement of CRP levels. All the data was collected on a predefined proforma. The data was entered and analyzed in SPSS Ver. 23.0.

Results: The mean age of patients was 45.5 l ± 10.64 years. There were 192 (55.7%) males and 153(44-3%) females. The mean duration of heart failure was 6.46 ± 3.53 hours. The mean CRP in these cases was 6.27 ± 4.70 mg/L. There were 153(44.3%) patients who had raised CRP while 192(55.7%) patients had normal CRP levels.

Conclusion: Increased CRP levels were seen in high number of cases and this may be established as significant risk factor for in hospital mortality. Particular attention should be given for prior management in presence of raised CRP.